If your dog's masses are oral papilloma, there are a few treatment options, although none are perfect. The animal's immune system is what rids the body of warts, so most papillomas will resolve if left untreated. But keep a close watch and make sure the papilloma does not get larger or begin bleeding because then there is a risk of a secondary bacterial infection. It can take months for them to completely resolve, so be patient.
Azithromycin therapy of papillomatosis in dogs: a prospective - NCBI
Generally the lifespan of warts caused by canine oral papillomavirus are usually self-limiting and usually regress after five to six months. Surgical removal and cryotherapy are used for removal, but they are usually left alone. Azithromycin has had positive results in the treatment of COPV, see link below. Regards Dr Callum Turner DVM
Painless Dog Wart Removal - YouTube
Once freezing has occurred, the tissue slowly dies and falls away. In some moist sites such as the mouth and the anus, the tissue may liquefy and look green and gangrenous. Usually all that is necessary is gentle bathing of the area to remove as much of the dead and sloughing tissue as necessary. There is sometimes a foul odor from the affected tissues. Despite the unpleasant appearance, there is no discomfort because of the temporary anesthetic effect on nerve endings. The patient is usually much happier than before. In more advanced or serious conditions, multiple cryotherapy treatments may be required. In many cases, it can be curative depending on the condition and the site. The technique is sometimes also used for the removal of aberrant or extra eyelashes (distichiasis). This procedure has a high success rate. Small warts and small skin tumors are usually cured with just one cryotherapy session. Tumors in the mouth often go into remission after one treatment and cause no further trouble.
Oral Papilloma Virus in Dogs - Pet Health Network
Dog warts are growths that are caused by the papilloma virus. The warts are most commonly found in the eye and mouth area. The warts are contagious and may be transmitted to other canines, but cannot be transmitted to humans. The warts are not a health threat and typically go away without treatment.In the vast majority of cases, treatment is not necessary, but in the rare cases of papilloma warts that persist for longer than 5 months, or the number of warts are so severe that the dog has problems even eating, then the surgical removal of one or a few warts has been known to speed up the rate at which the canine immune system clears the warts. Interferon has also been shown to speed the clearance of papilloma warts.